ISO 7303:2025
ISO 7303:2025 Simplified method for prediction of the oral bioaccessibility of metals and metalloids in soils
standard byInternational Organization for Standardization , 10/01/2025
standard byInternational Organization for Standardization , 10/01/2025
This document deals with the assessment of human exposure to metals and metalloids from ingestion of soil. It specifies a simplified method for the prediction of the oral bioaccessibility of metals and metalloids from contaminated soils.
u000bThe method is a chemical extraction using hydrochloric acid (HCl) and can be used at least for first-tier screening for prediction of the oral bioaccessibility of arsenic (As), cadmium (Cd) and lead (Pb) in soil samples. It produces extracts that are representative of the bioaccessible concentrations measured by using the validated unified bioaccessibility method (UBM) (ISO17924). More specifically, from the extractable concentrations of metals and metalloids by HCl, the predicted bioaccessibility in both the gastric and gastrointestinal phases is calculated using the equations and the prediction intervals provided in this document, and which have been derived from simple linear regressions of data obtained during validation studies.[2]
u000bNOTE The simplified method is applicable to prediction of the metals and metalloids bioaccessibility in soil with total concentrations range from 2mg/kg to 2600mg/kg for As, from 0,2mg/kg to 480mg/kg for Cd, and from 4mg/kg to 50000mg/kg for Pb.